We live at a time when a highly pathogenic viral epidemic appears to be spiraling out of control, with no clear resolution in sight.
Some pathogenic strains from epidemics have been shown to display this kind of hypermutator phenotype especially during the African epidemics due to serogroup A strains [30], [31].
One important factor regarding the use of Detectives as didactic material is the comprehensive coverage of topics within the context of a range of illnesses, including drug poisoning, food poisoning, epidemics, pathogenic diseases, strange or rare and hard-to-diagnose disorders, allergies, mass hysteria, and more.
The 2003 2004 highly pathogenic avian influenza epidemic caused by an A/H5N1 virus has become established in 8 Southeast Asian countries (1).
Moreover, the proteins encoded by these genes are conserved in two sequenced L. interrogans and ten epidemic pathogenic serovars in China.
There is information about the variation of pathogenic strains throughout epidemic outbreaks from host to host, but this again is a very special situation that, although extremely important for human health, does not help much in understanding the evolution of free living bacteria.
We therefore suggest the term "bad bugs" to avoid confusion between the epidemic, less pathogenic and non pathogenic species used in this study.
BTV serotypes 1, 2, 3, 4, 6, and 10 have a high pathogenic index and high epidemic potential (4 ).
The emergence of epidemic fungal pathogenic resistance to current antifungal drugs has increased the interest in developing alternative antibiotics from natural sources.
