Sentence examples for pathogenic change from inspiring English sources

In 2007, Kuwata et al. [11] reported that the intercalation of an anti-prion compound GN8 to the region N159-V189-T192-K194-E196 changeinhibit the processnic change profess of the prion.

We found that DNCB treatments promoted the differentiation of Th cells into Th2 cells, which appeared to provide a mechanistic basis for the predominant induction of DNCB-specific Abs as an important pathogenic change underlying the development of CHS.

Different from fibril-forming hot spots that are usually identified by observing the core of amyloid fibrils, we identified initial sites of conformational changes through reports in which a switch role is evident, such as experiments to inhibit the pathogenic change process (prion) and disease-related point mutations observed in clinical practice.

Any disturbance in the balance between these cells causes a pathogenic change in bone mass.

They screened two genes, representing candidates on the basis of their biology, without finding any potential pathogenic change [ 32].

A main challenge in NGS data analysis is the identification of the pathogenic change among the large list of variants.

The variations were regarded as pathogenic changes as long as they met the criteria of pathogenicity, i.e absence in 200 control individuals and the segregation with the disease phenotype within the family (Fig. 4).

Here we have used lens transcriptome profiling by microarray-hybridization and qPCR to identify pathogenic changes during cataract development in Mip-mutant (Lop/+) mice.

Therapeutic intervention using proteostasis/autophagy inducing drugs may mitigate the SHS exposure-mediated pathogenic changes initiating pediatric lung diseases such as bronchopulmonary dysplasia (BPD) or adult COPD-emphysema-like childhood condition.

Moreover, the pathogenic changes of both liver architecture and vascularisation in cirrhotic livers, as well as the lack of "true-to-life" in vitro models have impeded the development of an effective anti-fibrogenic drug.

Finding common pathogenic changes originating from these risks may lead to a new therapeutic strategy.