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Although much progress has been made in enhancing our understanding of NAFLD pathogenesis, development of pharmacologic treatments has been hindered by challenges in clinical trial enrollment and complexities in clinical trial design.
Genetic variability could also affect viral pathogenesis, development of vaccines, and development of efficacious therapeutic agents.
A recent study reported that leptin is involved in promoting the pathogenesis, development, and/or progression of RA [ 34].
As an initial step to reveal the pathogenesis development of PBC, in this study, we prepared PBC mouse model by consecutive injection of poly I C to C57BL/6 mice and quantitatively compared liver mitochondria proteome between model and control groups by iTRAQ technique.
This brief survey has touched upon the very first steps of HIV infection to illustrate how the pathogenesis, development of some types of anti-retroviral drugs and approaches to vaccine discovery have been aided by knowledge of receptors and entry processes.
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These findings further the understanding of NSCLC pathogenesis and development, and facilitate the development of lncRNA-directed diagnostics and therapeutics against this deadly disease.
These findings may help us to better understand the pathogenesis and development of NSCLC and facilitate the development of miRNA-directed diagnostics and therapeutics against this deadly disease.
Many LDAs have been reported to be involved in the pathogenesis and development of hematopoietic malignancies.
Based on results of the experiment we can suggest the significant role of stress in the pathogenesis and development of headache and neuroimmunological imbalance.
Therefore, early recognition of AKI, better understanding of its pathogenesis, and development of preventing strategies appear to be potential areas of improvement of patient's prognosis.
Even in cases where the disease origin is clear (e.g., asbestosis, silicosis and coal workers' pneumoconiosis (CWP)), it is often unclear what role the earth material plays in the mechanism of pathogenesis (disease development).
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