Sentence examples for pathogen presentation from inspiring English sources

At high latitudes, this strategy would not be feasible, as areas with less snow cover would be located at much longer distances from the denning sites compared to high altitude where areas with low snow cover are available in relatively close proximity (e.g. down slope, southerly aspect) Immune response genes, especially those involved in pathogen presentation, are highly polymorphic.

Modularization of peptide antigen from an unrelated pathogen for presentation on a modular virus-like particle (VLP) represents a new and promising approach to synthesize safe and efficacious vaccines.

Adaptive immunity involves the destruction of foreign pathogens and presentation of their peptide remains to T cells to begin the processes of antibody production by B cells, and "attack on site" natural killer (NK) cells and cytotoxic T cells.

Much interest is therefore focused on the cell type(s) involved in kick-starting the inflammatory response, in particular the prototypical antigen-presenting cell, the dendritic cell (DC) which, following infection, both takes up pathogen products for presentation to T cells and up-regulates a range of stimulatory molecules to drive T cell activation (Fig.  1).

In addition to antigen presentation, pathogen binding by DC-SIGN triggers signal transduction resulting in modulation of DC immune activation status.

This compartmentalization is essential for immune cell function, including pathogen recognition, antigen presentation and migration.

A promising alternative strategy that could simultaneously improve grape health and limit chemical use is to identify the unique genes or mechanisms from resistant species that could potentially confer resistance to the pathogen or lower presentation of symptoms.

Proteasome 26 subunit is involved in ATP dependent degradation of ubiquitinated proteins, which are instrumental in oxidative stress response and partakes in generating peptide fragments of invading pathogen for antigen presentation [ 51].

Macrophages and other phagocytic cells are important players in the innate immune system whose functions include phagocytosis (homeostatic cell clearance), antigen presentation (pathogen defense), and cytokine production (inflammatory responses).

Cells and molecules of the innate immune system play a fundamental role in the detection of pathogen-associated molecular patterns, in phagocytosis, pathogen destruction, antigen presentation to T-lymphocytes that drive the production of proinflammatory cytokines, and the subsequent activation of an effective adaptive immune response.

Mrc1+ cTMs are likely the principal myeloid environmental sentinels in the mouse heart as only Mrc1+ cells are macropinocytic, whereby MPs indiscriminately sample the local microenvironment for tissue damage and pathogen signatures before presentation of antigens to T-cells via MHCII molecules [ 9, 19].