Sentence examples for pathogen pattern from inspiring English sources
The oligonucleotide probes were designed to target eight immune-related genes that involve in antimicrobial activity, melanization, pathogen pattern recognition proteins, lysozyme and one housekeeping gene as an internal control.
Thus, TLR5 is the major pathogen pattern recognizing receptor of HCECs to initiate the inflammatory response toward P. aeruginosa.
The epithelium forms a physical barrier at the apical layer preventing microorganisms from entering the cellular layers that express pathogen pattern recognizing receptors such as TLR5 [28].
Smith et al. [16] reported that 3-oxo-C12-HSL induced activation of the pro-inflammatory signaling components Cox-2 and NF-κB in transformed cell lines however, this does not occur in primary cells in the absence of LPS neither does 3-oxo-C12-HSL act via known pathogen pattern recognition receptors [21].
Antimicrobial peptides, lysozyme, and pathogen pattern recognition polypeptides are commonly found in the sialotranscriptome of blood sucking arthropods.
Toll-like receptors (TLRs) are pathogen pattern recognition receptors that recognize bacterial and viral products, and other pathogens [ 8].
Based on the rationale that (i) hTectonin is an architectural homolog of GBP and (ii) as a pathogen pattern-recognition receptor, GBP interacts with CL5 [26], which is a homolog of the human ficolin, we performed yeast 2-hybrid analysis using hTectonin as bait and the three isoforms of ficolins (L-, H- and M-ficolin) as prey.
In an infection, the pattern recognition receptors (PRRs) of the macrophages recognize pathogen pattern-associated molecular patterns (PAMPs), leading to phagocytosis of the pathogen, release of cytokines and secretion of antimicrobial peptides.
The findings of the present study indicate that T1D may enhance the inflammatory responses of coronary artery to pathogen patterns.
The knowledge of pathogen patterns causing CAP as the basis for the selection of such treatment is therefore crucial.
The data underscore the need to understand local pathogen patterns, the recognition of which should drive decisions about the utility of these powerful molecular diagnostics.
