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Evaluating the unique differences in pathway and GO perturbations across pathogen conditions allowed the identification of plausible host pathogen interaction mechanisms.
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Mice were housed in filtered cages under specific-pathogen conditions and permitted unlimited access to food and water.
Immunodeficient mice were maintained under pathogen free conditions in individually ventilated cages (IVC) with free access to food and water.
Rats were housed three/cage for 2 weeks in Specific Pathogen Free conditions, until sacrifice.
The animals were housed under specific pathogen free conditions.
All animals were housed under standard (specific pathogen free) conditions.
The animals were fed standard laboratory chow and housed under specific pathogen free conditions.
They were manipulated under pathogen free conditions using laminar flux hoods.
All mice were housed in pathogen free conditions with free access to food and water.
Fully backcrossed Nod1 deficient mice were re-derived in specific pathogen free conditions at Taconic Farms.
Pathogen challenge conditions are described hereafter.
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