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Furthermore, the migraineurs showed a dysregulated brain topology, characterized by increased strength, path, and clustering coefficient.
In the current study we calculated for each network the node degree distribution, betweenesss centrality, shortest path and clustering coefficient for the quantification of the small-world properties.
First, we calculated topological properties of the 'interactomes', such as degree of connectivity, average shortest path and clustering coefficient [ 14].
Among methods solely based on gene/protein networks, a method using a random walk with restart (RWR) algorithm [22, 24, 25] is more dominant compared to other methods such as nearest neighbor, shortest path and clustering [26].
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Genetic interactions are best characterized by the shortest-path and clustering coefficient STMs.
In this study, we focused on the network parameters of connection strength, path length, and clustering coefficient [13].
Characteristic path lengths and clustering coefficients of RIGs have been modeled by a variant of small-world networks [19].
Average path lengths and clustering coefficients indicated that macaque and cat cortex exhibit small-world attributes, confirming several earlier reports on similar data sets (reviewed in [10]).
We investigated three main network properties for the PONs: degree and degree distribution, shortest path length, and clustering coefficient.
Usually such comparisons are performed in the context of global network properties like degree distribution, average path length, and clustering coefficient, and so forth.
Dramatic variation was also observed in the remaining properties, such as the network diameter, average degree, network density, average path length, and clustering coefficient.
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