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Small American manufacturers sprang up, and more than 250 patents were filed in two years.
Neither thiopurines nor tests for metabolites (substances produced by metabolism) were new when Prometheus's patents were filed in 1998.
Multiple patents were filed, but Mr. Shepherd-Barron's machine became generally known as the first cash dispenser when it was installed at a Barclays bank in a suburb north of London in June 1967.
"TiVo is attempting to assert its patents against technology disclosed and claimed in Motorola Mobility's patents, despite the fact that Motorola Mobility's patents were filed more than three years before TiVo's patents," Motorola said in a statement.
The patents were filed April 30.
All in all, 23 new patents were filed in the development of the EV1.
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Their patents are filed early in development and are being squeezed at both ends.
The third case, also involving six patents, was filed in federal court in Miami.
More patents are filed in German, which has far fewer speakers.
But Chinese patents are not widely cited for influencing innovation elsewhere, and only 6 percent of the country's patents are filed overseas, as well as in China.
Frontline patent examiners, working under tight time pressure, they say, tend to be outmatched by wealthy companies when patents are filed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com