"I thought that if I liked it at the USPTO, it would give me an entry into patent law.
The error here was propagated from the original substance submissions: a deprecated ChemSpider [3] entry, and patent sketches extracted by SCRIPDB [4].
A recent extensive review of HIV-1 entry inhibitors patented from 2004 2010, [ 20], revealed 35 small CCR5 antagonist molecules patented by 5 different pharmaceutical companies (Astra Zeneca, ViroChem Pharma, Anormed, Inc./Genzyme Corp., Euroscreen, and Ono Pharmaceuticals).
These companies enjoy big market shares and formidable barriers to entry, like patents, strong brand names and economies of scale, Ms. Sampson said from her office in Chicago.
There is a retort to that, too: that incumbents can use patents as barriers to entry, which is why America's antitrust regulators are showing interest in them.
But in a country like Nigeria, these sort of relationships, this kind of trust in a place where no one trusts anyone are more solid barriers to entry than patents.
Cefuroxime axetil practically was insoluble in water and introduced as Ceftin® by GSK in amorphous form and was protected by a couple of patents, which barred the entry of generic players for a reasonable period 45, 46.
For example in our experience in tuberculosis and malaria the patchiness of explicit chemistry connectivity between papers, patents and database entries impedes progress.
In January the European commission made dawn raids on the world's biggest drug firms, to gather evidence of possible anti-competitive behaviour This followed a £40m fine on AstraZeneca in 2005 for misusing the patent system to delay market entry of rivals to its ulcer drug, Losex.
The contrast procedure clearly singled out the multiword expression "bone age" as a very recent and meaningful entry in the patent database.
