For example, our data support the claim that courts are more likely to require disclosure of latent, as opposed to patent, defects.
In contrast to col27a1a, targeting of col27a1b with a translation-blocking morpholino (TBMO) or a splice-blocking morpholino (SBMO) did not yield patent defects in vertebral morphology, despite the induction of abnormal splicing by the latter (data not shown).
Uncorrected congenital heart disease (does NOT include patients with an isolated atrial or ventricular septal defect, patent ductus arteriosus, or patent foramen ovale).
The human ARCL1C syndrome includes pulmonary artery stenosis, pulmonary hypertension, atrial septal defects, patent foramen ovale, heart valve defects and a mild right ventricular hypertrophy in one case (Urban et al., 2009).
In the camel, heart diseases include pericarditis, vegetative valvular endocarditis, hypertrophic cardiomyopathy, necrotic myocarditis and congenital defects including septal defects, patent ductus arteriosus, transposition of the aorta and pulmonary artery, persistent aortic trunk, and persistent right aortic arch and sarcocystosis [ 1- 7].
Besides cardiac arrhythmias, manifestations of TS include congenital heart defects like ventricular septal defects, patent ductus arteriosus, hypertrophic cardiomyopathy and Tetralogy of Fallot [ 11].
The size and extent of variation in ventricular septal defect, patent ductus arteriosus, Tetralogy of Fallot, atrial septal defect, pulmonary stenosis, complete transposition of the great arteries, aorta, aorta velocity, pulmonary artery, and pulmonary artery velocity presented irregular change with gestational age.
Heart disease was categorized as follows: 1) congenital heart disease, including aortic valve stenosis, atrial septal defect, patent ductus arteriosus, Tetralogy of Fallot, pulmonary stenosis, complex congenital heart disease and others, or 2) acquired heart disease, including arrhythmia, cardiomyopathy, myocarditis, rheumatic heart disease, infective endocarditis, Kawasaki disease and others.
Cardiac CT currently represents a gold standard for assessment of the anatomy of the LA complex, LAA shapes and lobes, LA wall thickness, atrial septal anomalies such as septal defects, patent foramen ovale, and diverticula.
Ironically, all early reports of such complications described atrial septal defects, patent ductus arteriosus, and aortic coarctation as congenital cardiovascular malformations of MFS, none of which are considered typical manifestations of MFS today.
In the present study, we did not observe defects in mitochondrial respiration in ND/STZ mice, neither with pyruvate/glutamate nor with palmitoylcarnitine as substrates, while cardiac dysfunction was patent, suggesting that defects in mitochondrial respiration per se may not be the primary cause of cardiac dysfunction.
