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Four late graft occlusions occurred, with a 1-year cumulative primary patency rate of 77% and a secondary patency rate of 92%.
The five-year primary patency rate is at least similar to prosthetic above-knee bypass surgery.
However, the patency rate of our first-generation tubes after 3 months was only 50%.
Females had a statistically significant lower primary patency rate, i.e., 26 vs 45% (p-value = 0.01).
Primary assisted haemodynamic patency rate was calculated on intention to treat basis and for successfully treated cases.
The five year cumulative primary patency rate by means of life table analysis was 37.8 ± 6.67% (SE).
The main pathology behind low patency rate include thrombosis and graft/vessel hemodynamic mismatch, leading to intimal hyperplasia.
After implantation, pericyte-seeded TEVGs showed a significant higher patency rate than the unseeded control: 100% versus 38% (p < 0.05).
The primary assisted patency rate was 94, 91 and 65% at 6, 12, and 24 months, respectively.
The blood vessel patency rate was significantly higher than that of control group 8 weeks after implantation in rats and the endothelialization level was superior to control.
At 6 months the overall vessel patency rate on duplex imaging was 57%, improving to 64% in the group having a primarily successful procedure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com