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Methodological advances include experimental designs for complex and patchy, interacting sets of species, the importance of controls in experimental manipulations and methods for analyses of hierarchical scales of patterns and processes.
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A close look at the agents of self-assembly in living systems reveals a key aspect of the problem: Most biomolecular objects interact through directionally specific forces, so-called "patchy" interactions.
However, his track record when it comes to interacting with other cultures is patchy to say the least, and politicians around the world will no doubt be intrigued by the prospect of working with a man who once wrote a poem about the Turkish president having sex with a goat.
TRN neurons are well known to interact via inhibitory synapses but the specific intra-TRN circuits are unknown, so patchy expression may not be a good predictor of the effect of optogenetic suppression on overall TRN activity.
Appearance: Patchy.
Electricity is patchy.
Records are patchy.
Electricity supplies are patchy.
Still, compliance is patchy.
Quality is patchy, however.
Elsewhere standards are patchy.
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