The explanation appears to be that very scant, patchy loose bone or osteoid formed also around the control screws after 1 week, but then disappeared when resorption was not suppressed.
Multiple spots or patchy farfetched bone destruction, periosteal proliferation, fracture, and swollen surrounding soft tissue were present in X-ray images (Fig. 3a– b), emission computed tomography bone scans, high-resolution computed tomography (Fig. 3c), and positron emission tomography/computed tomography (Fig. 3d).
MR imaging of the patient's ankles 2 weeks later revealed bilateral calcaneal incomplete stress fractures, in addition to patchy areas of bone marrow edema in the medial talar head and posterolateral tibia.
Furthermore, we saw ectopic calcifications in the eye (Fig. 1O,P,Q) and the ethmoid plate cartilage (Fig. 1O,P), as well as patchy mineralization of craniofacial bone elements (Fig. 1O P′) and mineralization of the bulbus arteriosus – the outflow tract of the heart (Fig. 1R,S; supplementary material Fig. S1J,K).
Plain radiographic changes were cortical thinning, cortical bone loss, and patchy osteopenia.
There was whitish patchy marks (black arrows) observed in femoral bone tissues of OVX mice.
There is some evidence of primates living in Africa about 55m years ago, but the knowledge is patchy and comes only from a few bones and teeth.
The bilateral diffuse or patchy symmetric osteosclerosis of the major long bones, with relative epiphyseal sparing, associated with perirenal disease or aortic perivascular thickening, is virtually pathognomonic for ECD.
CT usually reveals a patchy radiopaque-radiolucent ill-defined lesion with cortical bone destruction, usually without periosteal reaction (Fig. 11).
When present, the amount of bone was generally small with a patchy distribution.
