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But its patchwork assembly is mitigated by the thematic coherence of Mr. Sondheim's work.
Equally intriguing to consider are the prospects that sterol biosynthesis and kinetic control of it evolved by a patchwork assembly with the individual members having undergone a duplication event followed by divergent evolution to give rise to the unique specificities.
Together with the pan-genomic evidence, it strongly demonstrates that most PAH-degrading strains share the same genetic sources and pathway evolution by patchwork assembly (assembly of existing pathways in new combinations), which has been systematically evaluated as highly successful [ 9].
In our previous study with M. vanbaalenii PYR-1, a fundamental building principle of the PAH-MN, a patchwork assembly of the phylogenetic modules, with a backward evolutionary direction from CAP via SCP to RCP, has been hypothesized on the basis of the functional association of the phylogenetic modules [ 9].
Hence, all the successful evolutionary trajectories were able to satisfy the functionally reversed growth of the PAH-MN: a patchwork assembly with a growth direction from CAP to RCP via SCP, essential to minimize the toxic effects of the activated PAH intermediates, which are produced in the RCP [ 9].
Even though it is possible that different processes might have been responsible for the build up of metabolic routes, a large body of data concerning both sequence comparison and experimental data on enzymes substrate specificity strongly supports one of them, that is the patchwork assembly theory [ 2].
Similar(53)
Moreover, Khoury's structure is a patchwork, an assembly of fragments that intersect and repeat or simply disappear.
What kind of a future do we have now?" Even if the workers have been toiling hard, the Longbridge plant, a 94-year-old sprawling patchwork of assembly shops interspersed with some advanced BMW facilities, has failed to improve efficiency.
What Graeber wants is a kind of decentralized socialism, with decisions made by a patchwork of local assemblies and coöperatives — at one point, he imagines "something vaguely like jury duty, except non-compulsory".
Unlike Tunisia or Egypt, where the powerful Ennahda and Muslim Brotherhood parties were the clear front-runners, Libya's vote is set to usher in a 200-strong national assembly filled with a more fragmented patchwork of politicians representing competing local interests.
Indeed, this genome is a patchwork of six independently derived strains with the assembly of six major chromosome arms representing only 101.3 Mb of the 137.8 Mb expected.
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