Sentence examples for patch component from inspiring English sources

Costa et al. found a nef consensus motif that binds the actin cortical patch component (AIP1) in vitro and in vivo [41].

The development of new fast-acting chemical inhibitors that target specific endocytic patch proteins may enable one to acutely arrest patches in specific stages of their maturation and provide new mechanistic insights into the functional roles of each patch component.

The mathematical details are set out in the Supplementary Information S1. Figure 5 shows how the within and between patch components of the host and vector reproductive numbers depend on the degree of host mixing if the vector population distribution is highly skewed.

Consistent with this view, Las17 GFP was initially reported to localize to the base of the invagination and not move inward with other patch components (Kaksonen et al. 2003).

An appropriate test can assure that there is no migration of API from the active portion of the patch to any of the patch components during storage and that the drug concentration is homogenous throughout the TDS.

Multicolor live imaging of patch components in yeast cells has become an incredibly powerful assay for defining the roles and dynamics of different endocytic proteins and the consequences of mutations or perturbations.

Moreover, it may be possible to reconstitute some of the steps in endocytosis in vitro and to develop single molecule assays to define the activities and interactions of early patch components.

The resulting grid was generalized by using a minimum threshold of 4 ha (or approximately 10 acres) which for the Teakettle Experimental Forest has been shown to be large enough to contain the three main patch components of mixed conifer forest: closed canopy, gap, and shrub patches (North and others 2002).

One immuno-EM study reported a marked enrichment of Arp2/3 complex compared to other patch components away from the membrane, which was interpreted to suggest that the growing barbed ends of actin filaments face the base of the invagination (Rodal et al. 2005b).

To facilitate this step, there may be patch components that help cluster and anchor myosin I at the base; one candidate for this role is Pan1, which binds myosin I through its C-terminal proline-rich domain (PRD) and increases the combined NPF activity of myosin I and Vrp1 (Barker et al. 2007).

These early studies set the stage for subsequent paradigm-shifting discoveries, in which two-color live-cell imaging of pairs of cortical patch components revealed that endocytic and actin machinery colocalize but arrive at sites of endocytosis at different times (Kaksonen et al. 2003).