Sentence examples for passive administration from inspiring English sources
A number of diseases are treated by passive administration of human proteins.
Strategies designed to blocking IL-1β by passive administration of inhibitors (mAbs, IL-1 receptor antagonist) have previously demonstrated efficacy in rheumatoid arthritis (RA).
Due to their stability in the gastric environment and avidity, passive administration of secretory immunoglobulin A (SIgA) antibodies (Ab) targeting protective Ag might be particularly relevant as a substitute or complement to current therapies.
Passive administration of antibodies (e.g., anti-serum or monoclonal antibodies) can be successfully used as treatments for infectious agents (e.g., human cytomegalovirus, HIV), chronic inflammation (e.g., anti-TNF), cancer (e.g., anti-HER2, anti-VEGF, anti-CD20), toxins (e.g., anti-ricin), and age-related diseases such as macular degeneration (e.g., anti-VEGF).
Passive administration of polyclonal antibodies against H5N1 has been shown to be protective in several non-primate and human models of infection [6].
Experimental studies in mice have also shown that passive administration of anti-cryptococcal mAbs prolongs survival and reduces fungal burden compared to control animals [32], [33].
This could be important in both vaccine design and in passive antibody administration.
Sex differences in nicotine's influence over overt behaviors (i.e. hypoactivity or behavioral sensitization) can be examined using passive drug administration models in male and female rats.
The fact that we were able to elicit AMPAR redistribution with passive drug administration or passive light-activation indicates the permissive nature of these events for addiction.
As a proof of principal, the passive intravenous administration of a mixture of these human broadly neutralizing MAbs to Rhesus macaques prior to intravenous or intravaginal challenge with SHIV indicates that the presence of neutralizing Abs prior to exposure can prevent infection [24], [25], [26], [27], [28], [29], [30].
Passive antibody administration protects severe combined immunodeficiency (SCID) mice against lethal Y. pestis infection (39).
