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After these two passes of the data, we went through each electropherogram trace by hand to ensure that peaks were correctly called and placed in the appropriate bins.
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would be identified and included in a 'first pass' of the data.
These networks were used to build related word lists encapsulating conceptual connections (e.g. church tower related to clock) so that during a secondary pass of the data, related network segments could be merged.
As a first pass of the data we focussed on gains occurring in a very high proportion of cases which included regions of chromosomes 3, 7, 8 and 20.
For each PASS, 90% of the data as historical at random is selected.
Our software systems should thus be seen as robust low-pass filters of the data with subsequent expert review of data flagged as 'bad' to be recommended.
Following temporal smoothing and low pass filtering of the data, all blocks were manually scored as being either usable or unusuable for analysis.
Digital low-pass filtering of the data is expected to increase the SNR performance further.
Band-pass filtering of the data reduces the high frequency physiological components.
Doing so minimizes the number of passes through the data set because of the Apriori principle, but requires the rule set to be parsed multiple times.
And the corresponding algorithms make multiples of passes over the data for finding the supports of candidate sequences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com