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So at an atemporal perspective, time simply does not pass, there is nothing about passage to know, and this is why passage poses no problem for immutable omniscience.
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The complex topology of protein channels and the transient nature of the ligand passage pose difficulties in the modeling of the ligand entry/escape pathways by canonical molecular dynamics simulations.
The passage of time poses another challenge to the recontact approach.
Many of these bars reach above the waterline and are easily visible, but a series of rods towards the lagoon side of the passage are submerged and pose a potential hazard to boats.
Though this 1939 work poses technical challenges — passages in double-stops, some fairly quick, are plentiful — it is less about artifice and surface dazzle than intensity and foreboding.
Instead he poses questions, cites passages from the classics, or uses apt analogies, and waits for his students to arrive at the right answers.
The longer lifecycles and potential requirement for multiple host passages to obtain stable knockins poses a significant challenge to implementing these tools, which may be insurmountable for many parasites.
Safe passage of pedicle screws at C2 poses challenges because of the proximity to the vertebral artery, size of the pedicles, and variations in the location of the foramen transversarium.
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In a few cases, Turkish authorities have blocked the passage of ships that they determined posed a danger to Istanbul, a city of 12 million whose Asian and European sides are divided by the 18-mile-long Bosporus.
Since the conductance of a vessel is proportional to the fourth power of the vessel radius (Hagen-Poiseulle law), a slightly reduced diameter would pose an obstacle to passage.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com