The phrase "passage over time" is correct and usable in written English.
It can be used to describe the process or experience of something changing or evolving as time progresses.
Example: "The passage over time has transformed the once bustling city into a quiet town."
Alternatives: "change over time" or "evolution over time."
PDX cells can then be passaged over time to form a renewable tissue resource.
Furthermore, there is a lack of knowledge regarding the outcomes of on-going auto-infection (sequential passaging) – over time does further interplay between host and pathogen result in increased fitness on that host line (spore production, infection efficiency etc).? Comparison of relative spore efficacy among isolates of Erysiphe graminis f.sp.sp
Then you continue, the delicacy of the chanced passages increasing over time, just as their scale declines.
b HRP was added to the top chamber, and HRP passage was monitored over time.
Similar results were also obtained in human fibroblasts where, surprisingly, an increased expression of the P21 gene (CTR passage 10 versus CTR passage 33) was observed over time) but not overexpression of the P16 gene).
And then we'll keep talking about the passage of time over and over again until so much time has passed that we'll stop existing as physical beings altogether!
Cells were passaged at near confluence, and were considered immortal when passaged over 50 times.
To date, transformed aortic cells has been passaged over 64 times over the span of 10 months without any change in morphology or growth characteristics.
It has been maintained in long term monolayer culture for 26 months, and passaged over 100 times (much greater than 300 population doublings).
Thus far, the genomes of only three avipoxviruses have been published; a pathogenic American strain of fowlpox virus (FPVUS) [ 9], an attenuated European strain of fowlpox virus derived from European FWPV HP1 passaged over 400 times in chick embryo fibroblasts (FP9) [ 10], and a virulent canarypox virus isolated from a canary (CNPVATCC VR-111) [ 11].
