Sentence examples for passage of substrates from inspiring English sources

Their function is to regulate paracellular passage of substrates across the BBB.

However, gap junctions have also been shown to "rescue" dying cells by the passage of substrates such as ATP, glucose, and ascorbic acid, as well as by inhibiting the passage of cytotoxic agents such as nitric oxide and others [ 5, 167, 168].

This study is also important from the drug discovery perspective, whose pace can be enhanced by apriori knowledge about the effects and location of length variations in relation to the active sites or changes in passage of substrates (small drug-like molecules).

The study of thickness of the porous layer onto the availability of enzyme showed that higher thickness hinders the passage of substrate into the pores, which results in lower activity.

Such structure was likely to facilitate the passage of substrate and the release of hydrogen gas as well as light penetration.

The α-barrel tapers to an almost closed conformation at the periplasmic end, necessitating a mechanism for channel opening to allow passage of the substrates, which range from bile salts and various antibiotics to secreted proteins [4].

27 Some AQPs have even been shown to allow passage of unconventional substrates, eg, arsenite or nitric oxide.

An N-terminal dileucine motif targets the MFSD8 protein to lysosomal membranes [ 38, 39] where it may control the passage of unknown substrates into or out of the lysosomes.

On the other hand, our TatAd data argue against a 'simple' channel role for TatA-type complexes, because the diameters are too small to allow the passage of larger substrates, such as E. coli TorA which is 90 kDa in size.

Such ADEP-induced pore opening might create a new substrate recognition area and may allow for the passage of larger protein substrates.

The passage of the unfolded substrate into the core is called translocation and necessarily occurs after deubiquitination.