Sentence examples similar to passage laboratory from inspiring English sources

The high-passage laboratory strain AD169 was used for infection (variant ATCC), as well as the FIX strain of HCMV (originally VR1814), which has been subjected to limited in vitro passage and whose genome is available as an infectious clone in a bacterial artificial chromosome (BAC) (Hahn et al., 2002; Murphy et al., 2003).

aReference strain is the highly passaged laboratory strain H87.

aReference strain 56Philipp is the highly passaged laboratory strain H87.

Previously, we characterized the transcriptional changes that occur upon transition from a FeHm-starved to a FeHm-replete environment in three unrelated fully sequenced H. influenzae isolates, the extensively passaged laboratory strain Rd KW20, the type b H. influenaze (Hib) strain 10810 and the invasive non-typeable (NTHi) strain R2866 [ 24, 25].

GT1 was originally isolated from skeletal muscle of a goat in 1980, and was subject to passage in laboratory conditions [ 15].

Traditional indirect sampling involving passage through laboratory animals in order to obtain parasite material for analysis presents significant ethical and practical drawbacks, and may result in sampling biases such as bottlenecking processes and/or host-induced selection pressures.

16 At present, it is possible to test for PZQ resistance using investigations into the dose of PZQ required to kill 50% of adult worms in vivo (ED50) or in vitro PZQ assays on adult worms derived from passage through laboratory rodents, 17, 18 with similar in vitro assays also used to test the comparative effectiveness of other drugs.

However, it has been reported that after numerous passages, the original features, infectivity and virulence of the parasite become attenuated, and they frequently require passages through laboratory animals, such as hamsters (reviewed in [ 13]).

Due to considerable in vitro passages of laboratory strains, the relevance of the M. tuberculosis H37Rv genome to clinical M. tuberculosis strains has been questioned [8].

The nasal passages of laboratory animals and man are complex, and lesions induced in the delicate nasal lining by inhaled air pollutants vary considerably in location and nature.

However, since the type d parent of Rd KW20 was originally isolated over 60 years ago [ 26, 27] and has undergone extensive passaging on laboratory media, this isolate is unlikely to be representative of clinically important strains and may even be altered in its regulation of gene expression.