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While the WT fibroblasts grew more slowly as they approached senescence, the immortalized BJ fibroblasts maintained a consistent population doubling time regardless of their passage age.
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Low-passage, age-matched cells were used for all experiments.
All of the loadings for the intercept factor are set to one, so that it equally influences all of the serial measurements; the loadings for the linear factor reflect the passage of age, and are equally spaced because of the uniform age between consecutive assessments; and the loadings for the second factor reflect the passage of age squared (Bollen and Curran, 2006).
We entertained cell passage, the age of the cell donor, and cell confluence as causes of clustering [ 25- 27].
The resulting VCAM-1 overexpression increases the adhesivity of monocytes to endothelial cells, and vascular permeability, speeding up the trans-endothelial passage of AGE-modified proteins (and AGE-LDL in particular).
Whether students, in later life, join Oprah's Book Club is a better indicator of middle school reading instruction than how they interpreted test passages at age 11.
Over at Wenhua Xiang, a meandering passage of aging apartment buildings that's lined, at street level, with trendy clothing stores, skateboard shops and even a sort-of punk hair salon, I met the rap artist Hu Xuan at Salvador's Coffee House.
When we recognize our place in an immensity of light-years and in the passage of ages, when we grasp the intricacy, beauty, and subtlety of life, then that soaring feeling, that sense of elation and humility combined, is surely spiritual..
When we recognize our place in an immensity of light-years and in the passage of ages, when we grasp the intricacy, beauty, and subtlety of life, then that soaring feeling, that sense of elation and humility combined, is surely spiritual .-- Carl Sagan.
Today the hill, a vast green expanse rising 197m with sweeping vistas of the surrounding countryside, remains a palpably sacred site with a wealth of remains including a Stone Age passage tomb (a narrow passage made of large stones containing multiple burial chambers) and prehistoric burial mounds up to 5,000 years old.
Particular keypoints should be taken into consideration (ie pharmacokinetic and physiological specificities, risk of false passage under the age of 6 years with capsules or tablets, presence of alcohol in some oral solution or bitter aroma…).
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