First-pass imaging of the heart occurred over 80 heart beats.
First-pass imaging of the wash-in of Gd-DTPA through the LV myocardium was performed in three short-axis imaging planes positioned in mid myocardial segments of the LV using a saturation-recovery turbo fast low-angle shot (FLASH) gradient echo sequence.
In the majority of cases, CE-MRA is performed as breath-hold, non-ECG-triggered "first pass" imaging (FP-MRA) after injection of an extracellular fluid (ECF) gadolinium based contrast agent (GBCA).
That these studies report initiating steady state imaging immediately after first pass imaging [ 21], or following the slow administration of small amount of additional contrast [ 22, 23], corroborates our assertion that rapid initiation of imaging postcontrast administration is vital to the success of gadobenate dimeglumine SS-MRA.
Both approaches allow single pass imaging, thereby reducing phototoxicity and the risk of acceptor photobleaching.
First-pass perfusion imaging of the heart at rest was performed using a saturation-recovery trueFISP sequence with a parallel imaging factor of 2. This allowed for an acquisition of four slices in a single breathhold.
Another characteristic feature of TSC is the lack of hypoperfusion on the first-pass imaging and at rest and of late enhancement on the delayed contrast sequence (Fig. 6) in the LV segments where there is STIR spotted oedema, which allows the differentiation from anterior ST elevation myocardial infarction.
From the recorded first-pass imaging movies, BST images and corresponding BST frequency distributions were produced.
To investigate the effect of sunitinib treatment on the function of tumor vasculature, first-pass imaging movies were recorded, and BST images and BST frequency distributions were produced.
The function of tumor vasculature was assessed by using a novel first-pass imaging method which involves recording movies of the dynamic distribution of a fluorescent vascular tracer after an intravenous bolus injection [ 33, 35, 39].
The value of first pass high temporal resolution imaging for the differentiation of benign and malignant lesions was studied in a direct comparison of steady-state dynamic MRI (30 s temporal resolution) and first-pass imaging (2 s temporal resolution) of induced mammary tumors in female rats by Helbich et al. [ 23].
