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Another characteristic feature of TSC is the lack of hypoperfusion on the first-pass imaging and at rest and of late enhancement on the delayed contrast sequence (Fig. 6) in the LV segments where there is STIR spotted oedema, which allows the differentiation from anterior ST elevation myocardial infarction.

Both approaches allow single pass imaging, thereby reducing phototoxicity and the risk of acceptor photobleaching.

In the majority of cases, CE-MRA is performed as breath-hold, non-ECG-triggered "first pass" imaging (FP-MRA) after injection of an extracellular fluid (ECF) gadolinium based contrast agent (GBCA).

That these studies report initiating steady state imaging immediately after first pass imaging [ 21], or following the slow administration of small amount of additional contrast [ 22, 23], corroborates our assertion that rapid initiation of imaging postcontrast administration is vital to the success of gadobenate dimeglumine SS-MRA.

Then two variations of 3D gradient echo based contrast enhanced MRA: (1) a time-resolved, low spatial resolution acquisition for first pass perfusion imaging and (2) a high spatial resolution acquisition for a breath-hold angiogram (Fig. 10).

From the recorded first-pass imaging movies, BST images and corresponding BST frequency distributions were produced.

To investigate the effect of sunitinib treatment on the function of tumor vasculature, first-pass imaging movies were recorded, and BST images and BST frequency distributions were produced.

The value of first pass high temporal resolution imaging for the differentiation of benign and malignant lesions was studied in a direct comparison of steady-state dynamic MRI (30 s temporal resolution) and first-pass imaging (2 s temporal resolution) of induced mammary tumors in female rats by Helbich et al. [ 23].

Morphologic parameters of tumor vascular networks were assessed from high-resolution transillumination images, and tumor blood supply time was assessed from first-pass imaging movies recorded after a bolus of 155 kDa tetramethylrhodamine isothiocyanate-labeled dextran had been administered intravenously.

According to comparative studies, HR-GBCAs allow superior enhancement and contrast delineation of lesions especially during steady-state imaging studies, whereas at first-pass imaging studies, a significant difference between HC-GBCA and HR-GBCA has not been demonstrated up to now.

First-pass imaging of the heart occurred over 80 heart beats.