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Point mutations of FLNa(M2474E) and FilGAP V734Y) confirm that these residues are critical for the binding partnering interaction in vivo (Figure 5A).
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The protein-protein interaction data, including interacting partners, interaction types and detection methods, were obtained from HPRD [ 24] and IntAct [ 25].
An in silico result predicted that transformation of trophozoite to cyst could be mediated through their cooperation with the protein partners interaction.
We do this by reciprocally coupling human subjects to a computationally implemented model of themselves, an invention we call Virtual Partner Interaction or VPI for short.
R132 is part of a cluster of basic amino acids suggested to be involved in the redox partner interaction with P450 Oxido Reductase (POR) [20].
p.R132C (g.782C>T) mutation is located in the loop connecting helixes C and D, and lies in a region involved in the redox partner interaction [20].
Partner interaction scores were set to zero if the questionnaire reported that no partner was present.
Thus this partner interaction is not independent of the AbdA-Exd interaction in this context either.
34 Subsample participants complete an adapted version of the Partner Interaction Questionnaire (PIQ).
Overall, participants submitted 4423 total entries noting with any partner interaction.
Together these data suggested that the phosphorylation of BCA2 by AKT was important to partner interaction.
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CEO of Professional Science Editing for Scientists @ prosciediting.com