Finally, we did not have data on blood cholesterol, an important risk factor for cardiovascular diseases, but even if such values were available, they would probably be, at least partly, intermediates in the association between diet and incidence of cardiovascular disease.
The oxidized S108C/L135C mutant forms a partly folded intermediate near pH 4, with a helical content comparable to that of the molten globule intermediate formed by the WT protein.
By contrast, upon lowering the temperature, the mean unfolding force from the partly unfolded intermediate state was found to markedly increase and the unfolding force distribution to broaden significantly, suggesting that the distance (xu) between the folded and transition states in the energy landscape along the pulling direction is decreased.
The cytochrome c oxidase complex is highly efficient at reducing oxygen to water, and it releases very few partly reduced intermediates; however small amounts of superoxide anion and peroxide are produced by the electron transport chain.
In the pectoral fin of the primitive ray-finned fish Polypterus, three elements constitute the proximal segment of the fin: two bony rods, the propterygium and the metapterygium, on the margins and an intermediate partly ossified cartilage, the mesopterygium.
The variations of [NO] with [air]/[H2] and also temperature indicate that NO is produced, at least partly, via the intermediate N2H.
A three-state unfolding of the MftR dimer may arise from native dimer N2 undergoing a transition to a partly unfolded dimeric intermediate I2, followed by the formation of unfolded monomers U (N2 ↔ I2 ↔ 2U).
Our multivariate models suggest that handwipes may at least partly serve as an intermediate variable between dust and serum levels.
As a result of this ensemble effect, the dehydrogenation rate to H4-NEC and NEC is expected to decrease on a surface partly covered with dehydrogenation intermediates.
Below 390 K, abstraction of the ethyl side chain might be suppressed by accumulated dehydrogenation intermediates, which partly cover the surface and thereby limit the number of potential reaction sites.
