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Because TGF- β1 is at least partly activated by proteolytic cleavage, we evaluated the total and active TGF- β1 levels for correlations with likely candidate proteinases involved in TGF- β1 activation and with PAI-1, a presumed secondary marker of TGF- β1 activity, in the gastric cancer homogenates (Table 3).
The hypothesis is in line with the possibility that effector T cells are partly activated in autoimmune diseases [ 5, 6], thus eliciting Treg activation.
No differences in the expression of CD11b or CD62L were observed (Table 3), indicating that the cells were only partly activated.
Our results indicate that PMN from SLE patients have altered function, are partly activated and are released abnormally from bone marrow.
Expression profile is suggestive of partly activated apoptosis (SMAC) and disturbances of intracellular signaling transduction cascades (down regulation of several cytokines, early genes, and regulatory proteins).
Recent studies have shown that TLRs are also expressed on the surface of a variety of tumor cells and partly activated by corresponding ligands.
Similar(49)
The mutation partly activates a cryptic splice site and results in a truncated mRNA transcript with a deletion of 150 nucleotides.
Whereas pseudowords may partly activate memory circuits for words and morphemes (Wennekers et al. 2006)—as reflected by a reduced activation but a still measurable superior temporal inferior frontal time delay unfamiliar noise sounds may not activate corresponding memory traces.
APLs interact with T-cell receptors and can partly activate T cells, causing a switch from Th1 to Th2 phenotype, or, in some cases, induce their transformation into anergic cells.
For example, the result 28 of the problem 7 × 4 shares its decade digit with the results 20, 21, and 24 associated with neighboring problems 5 × 4, 7 × 3, and 6 × 4, and because the respective semantic field nodes (5, 4), (7, 3), and (6, 4) are (weakly) activated by the problem 7 × 4, they also partly activate the 2-node in the decades field.
Several attempts and strategies have been adopted by the project to overcome this problem, and managed to partly activate communication around the project objectives.
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