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Astrolabe partitions groups of hosts into an overlapping hierarchy of zones in a manner similar to DNS.
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Each partition groups users or permissions with the same business categorization (e.g., all the users belonging to the same department, or all the permissions that support the execution of the same business process).
One-sided t-tests were performed to compare the genes in the same deacetylation partition groups and those in neighboring partition groups.
Among them, 141 pairs of genes are in the same deacetylation partition group, and 46 pairs of genes belong to neighboring deacetylation partition groups.
Among all the pairs, 1,811 pairs belong to the same deacetylation partition group, and 1,019 pairs are in the neighboring partition groups.
But for the genes in the neighboring deacetylation partition groups, the difference is not statistically significant.
This is further supported by the permutation results of the partition groups.
There are 1,113 deacetylation partition groups with more than one gene in total.
We also performed a one-sided t-test for correlations between the genes sharing regulators and deacetylation partition groups and those sharing regulators but in neighboring deacetylation partition groups, and the p-value was 3 × 10-4.
These results indicate that the deacetylation partition groups are enriched for genes of specific GO Slim terms.
In order to test whether there is function enrichment for the deacetylation partition groups, the following procedure was performed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com