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75– 77 Skin toxicity is most frequently seen as acneiform rash generally confined to the seborrhoeic areas; this particularly toxicity is a characteristic finding seen with most EGFR inhibitors, including panitumumab.
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Toxicity, particularly haematological toxicity, reported as the maximum WHO grade experienced by patients was mild.
However, classical WAI technique after surgery and chemotherapy is associated with high toxicities, particularly haematological toxicity, which leads to treatment interruptions.
Particularly, human toxicity potential (13 kg C6H6 eq).
This study reports a particularly favourable toxicity profile, with encouraging efficacy.
Haematologic and non-haematologic, particularly renal toxicity and neurotoxicity, were notably mild.
However, we must recognise the treatment risk after CRT, particularly cardiac toxicity.
Significant obstacles to the widespread adoption of miRNAs as clinical agents remain, particularly regarding toxicity, specificity and delivery [ 124].
However, microtubule destabilising VDAs appear to have some characteristic side effects, particularly cardiovascular toxicity (Beerepoot et al, 2006; van Heeckeren et al, 2006).
Synergistic and antagonistic actions are common occurrences among chemical contaminants and can be particularly important toxicity considerations in aquatic environments receiving runoff from several terrestrial sources.
In that study, survival, response rate and QOL results were superimposable, but pemetrexed was less toxic particularly for haematological toxicity and related hospitalisations and complications.
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