Diffuse staining for MR-1 was observed in ovarian cancer cells, particularly serous papillary ovarian cancer cells, compared with the benign control group.
Since it remains challenging to identify patients at risk, it has been discussed repeatedly, to which extent so called implants, representing extra-ovarian lesions coincidentally occurring in about 20% of particularly serous s-BOT cases, influence patients' prognosis [ 1, 4, 6].
In conclusion, we found that rs4954956 was associated with increased ovarian cancer risk, particularly for serous ovarian cancer.
The tumor marker CA-125 is frequently elevated in endometrial cancer and can be used to monitor response to treatment, particularly in serous cell cancer or advanced disease.
The present study has highlighted frequent MAL2 overexpression in ovarian carcinoma, particularly in serous tumours.
Particularly, the serous substances in the cochlear spaces were labeled strongly with an anti-MCP-1 antibody, suggesting that they may contain the released MCP-1/CCL2.
Here, we present evidence that PRL-3 is specifically upregulated in low-grade human ovarian cancers, particularly the serous cystadenocarcinoma and endometriod adenocarcinoma subtypes, but is undetectable in normal ovarian tissues.
As compared with the markers used previously, it possesses increased sensitivity for detecting ovarian cancer, especially the stage I disease (Havrilesky et al, 2008; Moore et al, 2008a), whereas the HE4 encoding gene WFDC2 is expressed particularly in serous and endometrioid ovarian cancer (Drapkin et al, 2005; Galgano et al, 2006).
Conclusions: A high proportion of borderline tumors of the ovary, particularly of the serous type, were associated with elevated CA 125 levels and abnormal ultrasonographic characteristics, although some tumors presented as simple cysts.
OBJECTIVES: Oligonucleotide array and tissue microarray analysis (TMA) by our group has revealed that folate binding protein (FOLR1) is overexpressed in some types of uterine cancer, particularly tumors with serous histology.
This up-regulation of miR-200 family members was particularly pronounced in serous and endometroid histotypes.
