Importantly, the results have implications for how we think about defining and operationalising models to predict risk of dementia, particularly in population based settings.
Research findings suggest that neighborhood deprivation is significantly associated with the metabolic syndrome, yet this remains a relatively understudied area particularly using population based data that includes a biracial cohort of black and white adults.
The present study also has several strengths, particularly regarding the large population based sample of adolescents and the high participation rate which might offer an opportunity to generalise the results to other adolescent populations as well.
The results suggest that routine MRI is not needed to predict risk of dementia in a population based setting, particularly in the first stages of screening such as differentiating between those who are and are not at risk.
It is particularly important to investigate LIPA in population based samples of older adults, because of the high proportion of time spent in light activity.
These limitations become particularly relevant when large MRI data sets from population based studies must be analysed, arguing for a need for automated measurement.
Our study was population based with high levels of case ascertainment, particularly of elderly patients.
Cancer registration particularly population-based ones remain rare in Ghana.
Our results strengthen the case for greater emphasis on preventive approaches, particularly population-based policies to reduce SBP and cholesterol.
Our results strengthen the case for greater emphasis on preventive approaches, particularly population-based policies to reduce blood pressure and cholesterol.
Compared to the extensive body of literature on the consequences of obesity in non-pregnant individuals [ 45– 48], research to date on the impact of obesity on reproductive outcomes is relatively scant, particularly population-based studies on extremes of BMI [ 5].
