The complexity of cartilage-bone interface and the differences between cartilage and subchondral bone layers, including both composition and biomechanical properties, particularly impede successful regenerative treatment (Pape et al. [2010]; Madry et al. [2010]; Orth et al. [2013]).
PrPc overexpression facilitated the intracerebral homing of systemically administered NPC, which was particularly impeded by PrP−/−.
The confusion over fee-charging and the need for integrated reporting registers are two systems issues that our study has highlighted that particularly impede effective delivery of integrated care.
Ronaldo is estimated to run about six miles per game, less than many forwards but still exhausting, particularly when impeded by nagging ailments.
Mr. Trichet also insisted that European governments do more to reduce debt and remove regulations and bureaucracy that impede growth, particularly in countries like Italy and Greece.
Though it doesn't take particularly large obstacles to impede a hobbit, a film adaptation of that J. R. R. Tolkien novel cleared a crucial hurdle on Friday as New Zealand's government passed a new labor bill promised to the "Hobbit" filmmakers, despite the objections of some legislators, Reuters reported.
Possible interactions with serum proteins may also impede activity, particularly when the peptides bind to abundant proteins in blood plasma such as human serum albumin (HSA).
The inability to draw appropriate conclusions on the basis of available evidence seems a particularly direct way to impede the adjustment of irrational, anxiogenic beliefs.
It has been suggested that poorer cognitive function impedes recovery, particularly in the context of CR, because it impacts on the patient's ability to learn or effectively respond to new information [ 60].
