These results were also well illustrated by box plots (medians were particularly differentiated) (Fig. 8).
The asphaltenes from the storage deposit are particularly differentiated with respect to the other two ones, featuring a higher polarity, a greater heteroatom content, and a lower aromaticity involving a smaller number of substituted aromatic structures.
Gut microbiome-derived metabolites particularly differentiated the PHD metabolome, while the symptomatic HD metabolome was increasingly influenced by metabolites that may reflect mutant huntingtin toxicity and neurodegeneration.
Peri and Requena (2010) focus on trade for Spanish provinces, 1995-2008, finding that immigration significantly raises trade – particularly for differentiated goods and for countries culturally distant from Spain.
Egger et al. (2012) use a quasi-experimental approach for 100 countries between 1991 and 2000, showing that highly concentrated skilled (or unskilled) migrants induce higher trade flows – particularly for differentiated goods.
These transcripts appear to be readily identifiable in tumours, particularly poorly differentiated, 'stem cell like' tumours such as EFT, but less so in normal tissues, which suggests functional roles in both development and oncogenesis.
Moreover, it was demonstrated that the DNA hypermethylation in cancers preferentially targets the development-associated polycomb group (PcG) proteins and other stemness related loci, and expression patterns of particularly poor differentiated tumors are similar to ESCs, including repression of PcS targets (PCGTs) [ 10– 13].
Likewise, in epidermal squamous cell carcinomas – particularly well-differentiated ones – many cells are reproductively sterile; for example, the cells comprising the pearls of keratinized squames – clearly less than one in four of these tumour cells are TICs.
Regarding carcinoma subtyping, negative or weak/focal immunostaining for K8 and K18 may indicate squamous cell differentiation, although strong expression of these keratins can occur particularly in poorly differentiated squamous cell carcinomas (see below, chapter "Keratins as diagnostic markers in tumor pathology").
Our study further indicates that the oral tooth shapes have divergently differentiated, particularly among the specialized scale eaters.
We found that Vav3 was overexpressed in 81% of human breast cancer specimens, particularly in poorly differentiated lesions.
