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In fish, it occurs in the form of methylmercury, which is known to damage neurons, particularly developing neurons.
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Developing neurons show particularly high expression of fgf11 and fgf14 (Luo et al. 2002; Wang et al. 2000), and the latter participates directly in neuronal signaling, axonal trafficking, and development of sodium channels required for neuronal excitability (Lou et al. 2005; Wang et al. 2002).
Similar to passive membrane properties, measurement of active membrane properties underlying AP formation and propagation allows for analysis of the electrophysiological profile of developing neurons and is particularly helpful in distinguishing pyramidal glutamatergic from inhibitory interneurons via their distinct AP shapes and firing patterns [ 6].
The glial sling is a migratory population of developing neurons.
Gärtner, A. et al. N-cadherin specifies first asymmetry in developing neurons.
Specifically, fluorescently labeled multi-signal live images of developing neurons from Drosophila larvae can aid in elucidating the biochemical mechanisms underlying the known morphological diversity of neuron types28.
Consistent with the protective function of MnSOD, developing APP/PS1 neurons have increased MnSOD protein and activity, indicating an adaptive response to oxidative stress in developing neurons.
Developing neurons express both Rac1 and Rac3.
SynIII and the neuron-specific CDK5 activator p35 consistently colocalized in developing neurons in vitro.
In susceptible, developing neurons activity suppression activates an apoptotic 'trigger'trigger
The developing neuron and its synaptic connections are important objects of investigation since they may be particularly vulnerable to pathogenic materials.
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