Sentence examples for particularly by modulating from inspiring English sources
The latter in turn determines whole-body insulin sensitivity, particularly by modulating skeletal muscle insulin responsiveness.
As peptidase expression is generally different between normal and tumour cells or tissues, there is the possibility of more specific targeting, particularly by modulating the N-terminal portion.
ILK upregulation and activation are related to β1 integrin signaling [ 1], and integrins may regulate gastric tumorigenesis, particularly by modulating adhesion and metastasis [ 58, 59].
Some bracovirus PTP genes play an important role in host immune alteration particularly by modulating PTP cell activity in hemocytes [ 32].
Tetraspanins play particularly important roles in cancer, by modulating tumor cell growth.
The relevance of these observations to basic aging research was reinforced by the finding that loss of insulin / insulin-like signaling (IIS), the most robust pro-longevity genetic manipulation currently known, partly influenced longevity by modulating HSP expression, particularly the low molecular weight small HSPs [ 10, 12, 13].
Altogether, our findings suggest that cells regulate LD integration in the ER by modulating ER lipid composition, particularly at sites of LD biogenesis and that FIT2 proteins may play a central role in this process.
They also influence de novo cholesterol synthesis by modulating the mevalonic pathway, particularly hydroxymethylglutaryl coenzyme A (HMG CoA) reductase [ 25].
Estrogen (17β-E2) accelerated βAPP trafficking and precludesmaximal Aβ generation within the TGN by modulating TGN phospholipid levels, particularly those of phosphatidylinositol. Therefore, fulvestrant, as estrogen blocker might activate phospholipid pathway to accelerate β-amyloid and aggravate AD.
Hypoxia, a feature common to most solid tumours, has been established as a promoter of angiogenesis by modulating expression of several mediators, particularly VEGF, cell adhesion molecules and surface receptors.
Indeed, it has been established that concurrent dietary intake, in particularly fibers, may exert a major influence on isoflavones metabolism, by modulating intestinal microflora (Xu et al 1995).
