Each type generates replacement cells for the particular tissue in which it is found.
This might involve giving them an extra dose of the genes that are highly active in that particular tissue type.
"Over the years, I just fell in love with this particular tissue and trying to understand it," she says.
Buried in the jelly of the umbilical cord are cells that are genetically identical to the baby, but which have not differentiated into any particular tissue type.
To illustrate how a disease manifests itself in a particular tissue, consider tauopathies, a class of neurodegenerative diseases associated with the pathological aggregation of τ protein within neurons.
Building on this hypothesis, we identified all diseases that form a significant subgraph in a particular tissue, following the procedure depicted in Fig. 4A.
In tissue engineering, it's unusual to tailor scaffold material to a particular tissue type; most researchers just rely on generic scaffolds.
Over the past several years, researchers have had great success using antibodies and other molecules to target drugs to cells of particular tissue types.
Taken together, we find that genes expressed in a particular tissue are not scattered randomly throughout the interactome, but tend to form a well-localized connected subnetwork.
Next, we analysed the ability of the panel of methods to identify reference cancer genes specifically annotated to particular tissue types (Fig. 2d).
The rate at which a chemical accumulates in a particular tissue is influenced by the blood flow to that tissue.
