This is because DNA microarrays allow observation of the presence of specific mRNA within the cell and in particular, time-series data allow measurements on how these change over time after a perturbation, or when following the cell cycle.
In particular, time-series data consisted of ten different experiments with 21 time points each; while knockout data included wild-type gene expression and gene expression after knocking out each one of the p genes.
In this vein, most of the comparative analyses of pertussis dynamics come from time series data of particular countries [ 3, 11].
Time series data, in particular, are receiving increased attention, since not only ordinary associations, but also other local and potentially time-delayed associations can be inferred from these datasets.
Furthermore, even if the time series data of particular metabolite shows the same qualitative pattern, see an example of E4P oscillation in Figure 7, the quantitative behavior demonstrates the differences in tenths of percentage.
For these studies, we zero-mean centered our time series data for each, particular, country or state as a whole for country/state-specific fixed effects.
However, in time series data, and, in particular, in conditional heteroscedastic time series, none of these assumptions hold and hence the behaviour of these measures is not that good as postulated for the bivariate Gaussian case.
Further, some other pattern can also be identified from the plot of time series data for a particular piezometer when collected for a long period, which can generally be considered as a representative of a particular aquifer or an area.
Finer-grained data, and in particular time series, would allow more detailed investigation of the causal nexus between economics and societal strife.
