Cardiolipin, in particular, regulates ETC activities of Complex I, III, IV and V, as well as regulating supercomplex formation (Fry and Green, 1980, 1981; Chicco and Sparagna, 2007; Bogdanov et al., 2008; Kocherginsky, 2008).
The vascular niche, in particular, regulates AML cell survival and cell cycling by both paracrine secretion and adhesive contact with endothelial cells.
HSF1 in particular regulates the transcription of many genes we also found increased by proteomics experiments (Mendillo et al., 2012).
Glucocorticoids (GCs) are pleiotropic adrenal steroid hormones that affect nearly all tissues of the body and, in particular, regulate metabolic, developmental, and stress-related processes (1, 2).
Hereat, repA and repC encode a helicase and an oriV binding protein, correspondingly, and the expression level of repC, in particular, regulates the extent of plasmid replication.
ANG1 and ANG2 phosphorylate the TIE2 receptor in endothelial cells and ANG2 in particular regulates proangiogenic gene expression in TEMs (Coffelt et al, 2010).
Mice either lacking endogenous CD19 expression or overexpressing a human CD19 transgene under control of the endogenous promoter revealed that CD19 is essential for the normal function of the BCR, and in particular regulates the threshold for its activation.
We hypothesize that the apparent under-representation of conidiation-related genes reflects a general lack of knowledge of how fungi in general and Cercospora species in particular regulate asexual development, and that many conidiation-related genes in C. zeae-maydis reside among the 4912 sequences that either had no similarity to known sequences or could not be annotated with the GO system.
As expected, most known matrix proteins were up-regulated to a greater extent at the juvenile stage, suggesting their particular roles regulating formation of either the inner aragonitic nacreous layer or the outer calcitic prismatic layer.
