"They show trade offs for society and tell you that there might be consequences of choosing a particular pathway".
They believe the prevalence of RAC1 mutation warrants development of therapies targeting that particular pathway.
This computation, which does not trace any particular pathway explicitly, circumvents the local-minima problem.
"If you haven't considered the role of AHPs in a particular pathway, you're unlikely to achieve your financial and quality goals".
The total variance along any particular pathway equals the product of the variance along the different segments of that pathway.
Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
Similarly WGCNA based clustering does not focus on a particular pathway but looks for modules of co-expressed genes that may belong to more than one pathway.
In conventional risk assessment, the onus, burden and levels of proof typically fall most heavily on those concerned about a particular pathway, or who prefer alternatives.
"What these results say is that we can reprogram all the major fat stores in humans by intervening in this particular pathway," explains Prof. Manolis Kellis.
One particular pathway involves a protein called tumor necrosis factor (TNF-alpha), which is produced in response to infection or trauma.
During the self-paced course, students may choose to pursue a particular pathway through course materials, based on their needs and preferences.
