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mRNA translation, in particular initiation, is tightly regulated by a number of mechanisms.
One of the recognized prokaryotic cell cycle theories is Cooper–Helmstetter (CH) theory which relates start of DNA replication to particular (initiation) cell mass, cell growth and division.
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In particular, the initiation part is the foundation of forming fracture network, and also basic parameter for analyzing fracture propagation.
Eukaryotic viruses resort to a vast array of strategies to divert the translation machinery in their favor, in particular, at initiation of translation.
Notches induce localized stress concentration effects that can affect many failure mechanisms, in particular the initiation and growth of short cracks under fatigue loads, significantly reducing the strength of structural components under service loads.
In our experimental set-up, the flow was driven by combined impinging jet and density perturbations forcing with the aim of determining their relative influence on the overall microburst behavior and, in particular, the initiation and structural evolution of the resulting vortex.
Of particular interest, initiation dependent decay targets a variety of heat shock proteins, including hsp70 and 90, and is dependent upon UPF1 and UPF2.
Our study highlights impaired chronic kidney disease, in particular after initiation of RRT, as a strong determinant of reduced HRQoL in FD.
An in-depth understanding of the structural basis of the HA-mediated membrane fusion mechanism, in particular the initiation, sequential events, and intermediates of the structural rearrangements, will undoubtedly expedite the discovery and development of novel anti-influenza fusion inhibitors.
Nevertheless, compatible isogamous gametes in fungi do not necessarily exhibit identical roles in cell fusion, and in particular the initiation of conjugation structures can be a behavior specific to only one mating type (Day, 1976).
Our study highlights chronic kidney disease, in particular after initiation of RRT, but even early in disease progression, as a strong determinant of reduced HRQoL in Fabry's disease.
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