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The estrogenic activity of phytoestrogens may also depend on their affinity for particular ERs in the body.
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In particular, Er-doped silicon-rich oxide structures showed interesting light-emitting properties[11 14].
In particular, ER stress plays an important role in the pathogenesis of diabetes.
The magnifications at which the SEM observation of the samples was made did not allow evidencing of any change in the morphology of the PSi due to the erbium deposition or any particular Er structure.
The use of rare earth elements, in particular Er and Yb, for the doping of Si and porous Si[8 10] has been a relevant research field due to the observed room temperature 1.54-μm luminescence.
Overexpression of certain particular ER chaperones in cell systems can protect cells against cell death caused by disturbances of ER homeostasis.
We extended the BOADICEA model of genetic susceptibility to breast cancer and ovarian cancer to incorporate breast tumour pathology information - in particular, ER status.
The particular ER model, which we use here, has n labelled nodes connected by m edges, which are randomly chosen from the n (n − 1 ) 2 possible edges.
However, the ability of current prediction algorithms to accurately assign novel proteins to subcellular localizations is somewhat limited, mainly due to localization and retention signals for endomembrane compartments, in particular ER, Golgi, endosomes, lysosomes or peroxisomes, being poorly understood.
These breast cancer biomarkers are also interdependent, however; in particular, ER expression is inversely correlated with abnormal p53 [ 15], overexpression of ERBB2 [ 15], high Ki-67 and nuclear grade, and poor patient prognosis [ 17].
In particular, ER-negative tumours showed significantly higher beta methylation values than ER-positive tumours at the three cg loci located within the first intron (cg04063345, cg15626350, cg00601836; p < 1.0 × 10−7 for all), which were in the same region as the p2 MVR assayed by pyrosequencing.
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