Suggestions(1)
Exact(6)
In addition, these results suggest that the physical presence of microparticles within stem cell aggregates does not compromise PSC differentiation, but in fact the choice of biomaterials can impact the propensity of stem cells to adopt particular differentiated cell phenotypes.
Such clustering can be readily explained assuming that the respective transcripts are indicative of common cell surface protein expression on particular differentiated cell types.
To confirm this result, we stained sections of the dorsal skin of BT and control mice with antibodies specific for marker proteins associated with particular differentiated layers of the epidermis.
This implies that no general patterns of gene mutation and no sequential set of gene modifications are expected, although each tumour, depending on its type and tissue of origin, may present more frequent mutations in the particular genes that are active in the particular differentiated tissue.
Based on our analyses, we suggest that the X chromosome provides an inferior environment for specialized genes with expression highly biased toward particular differentiated cell types.
Thus, when planning experiments to provide a particular differentiated cell type, consideration should be given to the most likely contaminants that may arise in reagents, cells and any test samples that might replicate in the differentiated cell types.
Similar(54)
This differential reactivity might be a consequence of a particular and differentiated exposure of each one of the antigens to the host immune system due to their specific location in the parasite [ 27, 34] or, alternatively, to the ability of the immune system to recognize antigens depending on the stage of the illness.
Developments in the generation of iPSCs have advanced significantly in the past 6 years ; however, concerns related to potential tumorigenicity, incomplete and inefficient terminal differentiation, as well as immunogenicity of iPSCs and in particular their differentiated progeny remains to be fully elucidated.
Our findings apply in particular to differentiated tissue macrophages such as alveolar macrophages which have similar attributes to the MDM we studied [16].
In particular, late differentiated CD4 T cells are associated with poorer vaccine responses (Derhovanessian et al., 2013; Moro-Garcia et al., 2012).
Several studies have confirmed the importance of the endosteal cells, in particular BMSC (differentiated or not into osteoblasts) and osteoclasts to support myeloma cell proliferation and survival [ 21, 22].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com