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This is consistent with class II allele specific recognition of particular altered self peptides in the lungs, with ensuing organ specific inflammatory disease depending on preferential peptide binding by allelic variants of class II molecules.
In particular, altered haemodynamics are implicated in the acute blood cell damage that leads to thromboembolic complications, with platelet activation being the underlying mechanism for cardioemboli formation in blood flow past mechanical heart valves (MHVs) and other blood re-circulating devices.
In particular, altered components of the COP9 signalosome have been detected in Smith-Magenis syndrome [29], [31], Down syndrome [33], Alzheimer's disease and Parkinson's disease [34], Machado-Joseph neurodegenerative disease [36], [37], and X-linked mental retardation syndrome [38], [39].
In particular, altered metabolism and oxidative stress may be caused by animal death.
Further, this initial expansion of ectopic lipid levels during steatosis development tends to be associated with progressive metabolic dysregulation and, in particular, altered hepatic insulin resistance and the development of inflammation.
In particular, altered αvβ3 integrin expression correlates with mammary tumorigenesis, particularly the processes of breast cancer cell invasion and metastasis [ 25, 27- 31], raising the possibility that differential integrin expression may contribute to the tumor promoting activities of TGF-β.
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While De Niro has often been slammed for falling short of his own storied career highs, it would be presumptuous to speculate about how closely he identifies with this particular alter ego.
In particular, altering the dimensionality of the embedding space d, the average number of "onyms" per color node (i.e., the average node degree), the threshold angle between "onyms", as well as the number of color nodes, did not affect the quality of the reconstruction in a wide range of parameters.
For any given ego, a particular alter can be in only one mutually exclusive category that is, spouse, sibling, friend, coworker, or neighbour.
In particular, altering the immunogenicity status of a protein can have a significant downstream impact on the effectiveness of a product as a potential therapeutic [ 36].
Because of their important role in accelerating nutrient cycling, grasshoppers can influence plant community composition and, in particular, alter the abundance and species richness of plant species (Belovsky and Slade, 2000).
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