Sentence examples for particles to target from inspiring English sources
In a breakthrough study, a team of Canadian researchers used virus-derived particles to target the blood cancer cells, successfully killing human cancer cells in a laboratory setting and eradicating the disease entirely in mice.
Virus-coated solid surfaces could also be used in vivo for highly site-specific delivery of viral particles to target tissues or cells through the direct application of virus-coated solid surfaces to target sites.
The two prevalent approaches for achieving cell-type-specific expression are to use a cell-type-specific promoter to control recombinant gene expression or to modify a virus vector particle to target gene transfer to a specific cell type.
Wadajkar and co-workers reported the development of magnetic-based core shell particles (MBCSPs) to target melanoma skin cancer cells B16F10 (Wadajkar et al. 2012).
Varying the target cell or virus concentration has some effect on the infectivity of HIV-1 [ 1, 2], but more important enhancements have been achieved by increasing particle absorption to target cells through the addition of polybrene [ 7], by spinoculation [ 10], by Magnetofection [ 4], or with the help of CD44 MicroBeads [ 11].
Based on these findings, it is suggested that LNC particles are able to target the drug to the brain tissue and reduce the tumor size.
The magnetic separation provides suitable route for online separation, where particles with affinity to target species are mixed with the heterogeneous solution.
High pressure liquid chromatography (HPLC) of tumor tissue confirmed that APMS-MB-DOX particles delivered DOX to target tissue.
This results in the uni-directional movement of all viral particles from infected to target cells, presumably using myosin II controlled retrograde flow of actin and cognate Env-receptor interactions (Fig. 3b1).
According to target particles and objects, it was shown that the appropriate technique must be selected.
Ultimately, the ability to target particles to different parts of the cell nucleus may start to impact on models available for chromosome aberration formation and chromosomal organisation and mechanisms underlying genomic instability.
