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This paper focuses on how fine particles are processed in a fluidized/spouted bed coater without agglomeration and what kinds of functions are desired for particulate dosage forms, in order to preview the future contributions of fluidization technology in pharmaceutical dosage form development.
In all other proteins of the photosynthetic pathway real particles are processed.
Ribosome biogenesis is a complex biological process during which pre-ribosome particles are processed to mature functional ribosome subunits.
In addition, it will be important to determine how internalized particles are processed; if they are targeted to lysosomes for degradation or are small enough to enter the nucleus or interact with other cellular organelles such as mitochondria, how will this affect drug efficacy or potential cytotoxicity?
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Another question investigators are examining is whether the particles were processed to diminish their natural affinity to stick together and float less freely.
What are the strategies to fabricate and encode gel particles, and how can particles be processed and decoded after the assay?
Total protein content was determined using the BCA colorimetric assay (ThermoFisher Scientific, USA) and empty PLGA particles were processed in a similar manner and used as a blank.
Because our primary interest was to focus on the ecology and discovery of RNA viruses, enriched viral particles were processed for the preparation of total viral RNA.
Selected low-defocus and minicell particles were processed together.
The particles were processed and analyzed using the EMAN2, SPARX, XMIPP and CoAn software packages.
Affinity purified pre-40S particles were processed for mass spectrometric analysis as described earlier (Altvater et al., 2012).
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