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Hines explains that this process is executed with the gene gun, a biolistic particle delivery system.
The cancer therapy by CASP3*-LENA may be more applicable to solid tumors due to the current technological limit in particle delivery.
Sustained and localized viral particle delivery was achieved over 2 months in vitro.
There were increases in airflow, particle deposition in the 3D model, and particle delivery to the diseased regions for the heterogeneous cases compared to the homogeneous cases.
It also offers an exciting possibility of designing size-based polymer particle delivery system to modulate immune response.
A SN38 loaded silica-lipid hybrid (SN38-SLH) particle delivery system was prepared by lyophilisation of mesoporous silica nanoparticle stabilised lipid emulsions.
We show that particle anisotropy promotes alignment and ordering even in the presence of flow, and can be used to increase the efficiency of particle delivery and sorting.
For investigations related to radiation risk, the effect of single particle traversals are paramount, therefore particle counting and single particle delivery are essential.
In addition, localized particle delivery augmented distribution in the loco-regional tissue basin where tumor burden predominates, while renal toxicity compared to standard intravenous CDDP was significantly reduced.
A polymer particle delivery platform made from the blend of three polymers, poly(lactic-co-glycolic acid) (PLGA) and two random pH-sensitive copolymers, were developed.
The efficiencies of small particle delivery (%<4.7 microm) were as follows, LC Plus = Acorn II (85%) > UpDraft (75%).
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