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To address this, we compared known characteristics of participating cases and potentially eligible, non-participating cases and found no difference between the two groups with respect to race, gender and urban versus rural residency.
Additionally, the proportion of Whites tended to be higher among the participating cases in the published case-control studies compared to the proportion of Whites among the non-participating cases or in cancer registries.
Blood samples were available from all participating cases.
In total, 523 participating cases and 1057 controls reported themselves as post-menopausal.
The characteristics of participating cases and controls are summarized in Table 1.
In addition, the participating cases provided blood samples for serological and genetic analyses.
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Control subjects had to be unrelated to participating case subjects and not carry the 22q11 deletion.
For every participating case, one age-matched control was randomly selected from patients registered with the case's general practitioner.
Reliability of these items will be assessed by comparing information collected from participating case and control mothers and their respective sons.
When we compared participating and non-participating cases and controls, we found that participation rates were higher for CML cases and did not differ by year of diagnosis.
Four private laboratories, covering entire Switzerland and diagnosing about one-third of all notified cases, participated in case recruitment from 21st December 2012 until 24th January 2013.
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