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5. line 247: "This RING finger has lost its ability to bind to zinc ions …" This phrase appears too speculative since there are atypical zinc-chelating residues (like 3His-Asp as in adiponectin receptors (http://www.nature.com/nature/journal/v520/n7547/fig_tab/nature14301_SF4.html), where a water molecule participates to stabilize zinc binding).
Similar(58)
We therefore demonstrate here that, while microtubules form the rails that are essential for active transport of endosomes, actin filaments participate to stabilize the movement.
In the HTH motif the hydrophobic residues belonging to the amphipathic α4-helix participate to stabilizing interactions with the α5-helix, while the three polar/charged residues Gln148, Lys156 and Lys159 are exposed to solvent, free to contact any binding partner [27], [57].
At last year's Group of 20 meetings in London, the participating countries agreed to stabilize the international banking system and to stimulate the world economy.
The π⋯π stacking and CH⋯π interactions participate in a cooperative way to stabilize the supramolecular architecture.
It was found to stabilize membrane microdomains, to participate in cell adhesion and cell migration, and to block virus budding [ 35– 35].
A proline at every third position serves to stabilize the structure [ 20], and also participates in hydrogen bonds as well as in hydrophobic interactions [ 21].
To stabilize?
She began to stabilize.
I'm trying to stabilize your city.
Within hours, Emma began to stabilize.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com