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LSD1 represses hTERT transcription via demethylating H3-K4 inormalandand cancerous cells, and together with HDACs, participates in the establishment of a stable repression state of the hTERT gene in normal or differentiated malignant cells.
By directly demethylating H3-K4 and indirectly promoting H3 acetylation associated with the hTERT core promoter, LSD1 participates in the establishment of a stable repression state of the hTERT gene in human normal or differentiated malignant cells.
To further determine whether ZNF93 directly participates in the establishment of the resistant phenotype, we transfected the ET-743 and PM00104 sensitive cell line CS-1 with a ZNF93 expression vector and generated stable cell line which overexpress ZNF93 (Figure 6D).
Annexin participates in the establishment of inflammation and the immune response.
MCD1 is present during DNA replication and participates in the establishment of sister chromatid cohesion [ 30].
NFI-C activates p53 and participates in the establishment of milk protein gene expression during pregnancy [ 13].
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Britain will not participate in the establishment of any European public prosecutor.
Alternatively, the very uncertainty of this moment may offer a unique opportunity to all those factions jockeying for power to participate in the establishment of representative government.
In accordance with its policy of neutrality, Sweden did not apply for membership in the European Economic Community EECC), although it did pursue its policy of liberalizing trade by participating in the establishment of the European Free Trade Association (EFTA) in 1959.
First, those messages authenticate the core node and the sensors and then only the trust nodes will participate in the establishment of the secure channels.
In the 1940s, Prof. Tao participated in the establishment of Shanghai Datong Chemical Industry Factory and Shanghai Yixin Chemical Manufacturing Factory, which was a pioneering contribution to chemical reagent industry in China.
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