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Due to its ability to induce apoptosis in Fas (APO-1, CD95) expressing cells, Fas ligand participates in essential effector functions of the immune system.
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Lee also directed his energies to founding the APA's Division of Psychoanalysis in which he continued to participate in essential roles.
In the following review, we describe the use of solution NMR techniques designed to probe various timescales of molecular motions and detail examples in which motions play a role in propagating catalytic effects from the active site and directly participate in essential aspects of enzyme function.
While the significance of this finding is not clear, these metals all participate in essential cellular function.
Many miRNAs are conserved in sequence between distantly related organisms, suggesting that these molecules participate in essential processes.
In addition, these single copy genes were highly conserved and were found to participate in essential housekeeping functions.
This type of composite functional modules was compact in structure, and was found to participate in essential cell processes such as oxidative phosphorylation and RNA splicing.
We detected 15 CT-PPI modules that participated in essential cell processes including the oxidative phosphorylation pathway, RNA splicing, and DNA-dependent positive transcription regulation.
BMP1/tolloid family metalloproteinases also participate in essential developmental processes such as dorsal ventral patterning, heart development, TGFβ (transforming growth factor β) signalling and neurogenesis [ 36, 37].
Given the fact that G4 DNA structures participate in essential biological processes, the formation of these structures is likely to be actively modulated during the embryogenesis and differentiation in a similar way as the regulation of DNA and histone methylation.
DUSP22, also known as JNK pathway-associated phosphatase (JKAP), is expressed in various types of tissues and organs (Chen et al., 2009), including the hippocampus (Hawrylycz et al., 2012), suggesting that it may participate in essential biological processes.
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